Vulvar and Vaginal Premalignant Lesions

What are Vulvar and Vaginal Premalignant Lesions (VPVL)?
Vulvar and vaginal premalignant lesions are cellular changes on the outer parts of the female reproductive organs or the vaginal lining. These lesions are often associated with HPV (Human Papillomavirus) infection and can potentially develop into cancer. The most common subtypes of VPVL are called vulvar intraepithelial neoplasia (VIN) and vaginal intraepithelial neoplasia (VAIN).
VPVL Symptoms and Diagnosis
VPVL is usually asymptomatic and is usually detected during a routine gynecological examination or HPV screening. However, when symptoms do occur, they may include itching, burning, pain, vaginal discharge, and abnormal lesions in the external genitalia. Diagnosis is usually made by vulvoscopy, colposcopy, and biopsy.
VPVL Treatment Methods
Treatment of VPVL varies depending on the size and extent of the lesion and the risk of cancer. Treatment options may include surgical excision, laser surgery, radiotherapy, topical medications and immunotherapy. The treatment plan is usually based on the patient's general health, age, and the characteristics of the lesion.
Prevention of Vulvar and Vaginal Premalignant Lesions
Measures such as regular gynecological examinations, HPV vaccination, smoking cessation and sexual hygiene can be taken to prevent VPVL. In addition, prevention and protection against sexually transmitted infections are also important in reducing the risk of VPVL.
The Importance of Early Diagnosis and Treatment
Early detection and treatment of vulvar and vaginal premalignant lesions prevents disease progression and reduces the risk of cancer. Therefore, regular gynecological examinations and HPV screenings are important. If any symptoms are noticed or risk factors are present, a specialist should be consulted immediately.
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